ncRNA name | C3 siRNA |
ncRNA Category | siRNA |
Disease name | age-related macular degeneration (AMD) |
Species | Mus musculus |
Tissues/Cell_line | retinas |
Methods | immunohistochemistry, in situ hybridization, qRT-PCR |
Expression pattern | associated |
Functional description | Local suppression of C3 expression using siRNA inhibited complement activation and deposition, and reduced cell death. |
PubMed ID | 28605809 |
Year | 2017 |
Title | Retinal Macrophages Synthesize C3 and Activate Complement in AMD and in Models of Focal Retinal Degeneration. |
Drug-related ncRNA | NO |
Copyright © Institution of Biomedical Big Data, Wenzhou Medical University All rights reserved.